TABLE 1.
Population demographics of the study subjects
| Parameter | Value for drug group
|
||
|---|---|---|---|
| Levofloxacin (n = 10) | Gatifloxacin (n = 10) | Moxifloxacin (n = 9) | |
| No of patientsa | |||
| Male | 8 | 9 | 8 |
| Female | 2 | 1 | 1 |
| Age (yr)a | 44 (30-54) | 34 (23-58) | 35 (18-46) |
| Wt (kg)a | 56 (41-66) | 56 (45-66) | 56 (43-69) |
| SCRb (mg/dl)a | 0.9 (0.5-1.3) | 0.9 (0.6-1.0) | 0.9 (0.7-1.2) |
| CLCR (ml/min)a | 79 (51-125) | 81 (61-107) | 96 (61-117) |
| Dose (mg) | 1,000 | 400 | 400 |
| Dose (mg/kg)a | 18.0 (15.3-24.0) | 7.2 (6.1-9.0) | 7.2 (5.8-9.3) |
a
Median (range).
b
SCR, serum creatinine.