TABLE 2.

MIC distributions for ceftaroline, ME1036, and four other β-lactams tested against a collection of 152 CA-MRSA strains isolated in the United States

Antimicrobial agent	No. of strains (cumulative %) inhibited at a MIC (μg/ml) of:
	≤0.06	0.12	0.25	0.5	1	2	4	8	16
ME1036	16 (10.5)	106 (80.3)	26 (97.4)	4 (100.0)	0 (100.0)	0 (100.0)	0 (100.0)	0 (100.0)	0 (100.0)
Ceftaroline	0 (0.0)	0 (0.0)	1 (0.7)	148 (98.0)	3 (100.0)	0 (100.0)	0 (100.0)	0 (100.0)	0 (100.0)
Ceftriaxone	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	0 (0.0)	2 (1.3)
Imipenem	−a	−	−	139 (91.4)	9 (97.4)	4 (100.0)	0 (100.0)	0 (100.0)	0 (100.0)
Meropenem	−	−	−	9 (5.9)	22 (20.4)	106 (90.1)	12 (98.0)	3 (100.0)	0 (100.0)
Amoxicillin-clavulanate	−	−	0 (0.0)	0 (0.0)	0 (0.0)	1 (0.7)	2 (1.3)	121 (80.9)	−

^a−, untested dilution concentration.