. 2008 Jan 7;52(3):1182–1183. doi: 10.1128/AAC.01332-07

TABLE 2.

In vitro activities of AR-709 against S. pneumoniae strains with various resistance patterns

Resistance pattern^a	No. of strains	In vitro activity of AR-709 (mg/liter)
Resistance pattern^a	No. of strains	MIC₅₀	MIC₉₀	MIC range
Penicillin S	63	≤0.015	≤0.015	≤0.015-0.25
Penicillin I	30	0.03	0.12	≤0.015-0.25
Penicillin R	58	0.06	0.25	≤0.015-0.5
Cotrimoxazole S	76	≤0.015	0.03	≤0.015-0.06
Cotrimoxazole I	16	≤0.015	0.06	≤0.015-0.25
Cotrimoxazole R	59	0.12	0.25	0.03-0.5
Azithromycin S	94	≤0.015	0.12	≤0.015-0.25
Azithromycin R	57	0.06	0.25	≤0.015-0.5
Amox/clav S	92	≤0.015	0.06	≤0.015-0.25
Amox/clav R	59	0.06	0.25	0.03-0.5
Multidrug resistant	26	0.12	0.25	0.03-0.5

S, I, and R, susceptible, intermediate, and resistant; amox/clav, amoxicillin-clavulanic acid; multidrug resistant, resistant to penicillin, cotrimoxazole, azithromycin, and amoxicillin-clavulanic acid.