TABLE 1.

Antibacterial activities of MIP-3α, its C-terminal peptide, and other antimicrobial peptides determined by various methods

Peptide or protein	E. coli					S. aureus				Reference(s)
	MIC (μg/ml)	MBC (μg/ml)	LD50d (μg/ml)	LD90 (μg/ml)	Lethal concn (μg/ml)	MIC (μg/ml)	MBC (μg/ml)	LD50 (μg/ml)	LD90 (μg/ml)
MIP-3α peptide51-70a	12.5	15.0, ≤1.1b				63.0	63.0, 4.7b
MIP-3α proteinb			0.07-0.53c	0.3				0.3	10-40c	23, 27, 76
MIP-3α59-70b			3.2							23
Bovine lactoferricina	50					100				69
Indolicidina	20	20				10	10			66
Magainin 2a	20					>100				68
Tritrpticina	20	20				10-20	20			66
IL-8 peptide53-72					147.4c					6

^aDetermined by a microdilution assay.

^bDetermined by a colony count assay conducted under low-salt conditions and with 10 mM potassium phosphate, which commonly yield higher activity values.

^cSome of these numbers had to be interpolated from figures.

^dLD₅₀, 50% lethal dose.