TABLE 1.
Aminoglycoside MICs and EC50s for serovars Virchow and Typhimurium in natural and acidic LB brotha
| Antibiotic | Serovar Virchow
|
Serovar Typhimurium
|
||||||
|---|---|---|---|---|---|---|---|---|
| MIC
|
EC50
|
MIC
|
EC50
|
|||||
| pH 7.0 | pH 5.7 | pH 7.0 | pH 5.7 | pH 7.0 | pH 5.7 | pH 7.0 | pH 5.7 | |
| Gentamicin | 8 | 125 | 2.0 (0.5) | 85 (7) | 4 | 125 | 1.0 (0.5) | 34 (5) |
| Kanamycin | 16 | 250 | 6.5 (1.5) | 130 (14) | 8 | 250 | 3.5 (2.5) | 29 (6) |
| Tobramycin | 8 | 250 | 2.5 (1.5) | 75 (7) | 4 | 125 | 1.0 (0.5) | 19 (6) |
a
EC50s were measured at 1 h; standard deviations are shown in parentheses. All data are mean concentrations (μg ml−1) from three experiments.