TABLE 2.
Hemoglobin, albumin, and amikacin concentrations in groups 1 to 4a
| Group | Hemoglobin concn (g/dl) | Albumin concn (g/liter) | Amikacin concn (mg/liter [range]) at:
|
|||
|---|---|---|---|---|---|---|
| 10 min | 60 min | 90 min | 150 min | |||
| 1 | 6.8 (6.0-7.7) | 22.1 (20.0-29.2) | 93.8 (88.6-102.0) | 8.7 (7.9-10.3) | 8.3 (7.4-9.9) | 5.7 (5.1-6.6) |
| 2 | 7.2 (6.7-8.6) | 21.6 (10.9-33.7) | 94.6 (87.6-115.2) | 3.8 (3.7-4.8) | 3.4 (3.4-4.5) | 2.9 (2.8-3.4) |
| 3 | 6.9 (5.7-8.3) | 19.9 (12.8-32.5) | 47.4b (46.1-52.3) | 4.5 (3.9-6.6) | 4.1 (3.6-6.5) | 2.9 (2.8-3.9) |
| 4 | 7.1 (6.6-8.3) | 21.4 (14.1-38.7) | 78.3 (68.9-90.0) | 59.1 (56.9-71.4) | 60.5 (43.6-71.6) | 34.7 (20.7-38.6) |
a
The concentration at 10 min is an adjusted concentration. The concentration in the mixing chamber was measured immediately prior to the start of circulation through the CVVH circuit. This value was then adjusted for the additional volume of the circuit, assuming an instantaneous distribution throughout the circulating volume.
b
P < 0.05 compared with the results for group 1 and P < 0.05 compared with the results for group 2.