TABLE 1.

S. pneumoniae MIC data for AR-709 and comparator antimicrobial agents

Drug	MIC (μg/ml)			% Resistance
	Range	50%	90%
AR-709	≤0.008-1	0.25	0.5	NAb
Erythromycin	≤0.03->32	8	>32	83.5
Penicillin	≤0.03-8	4	4	85.7
Cefotaxime	≤0.03-16	1	2	41.1
Amoxicillin	≤0.03->8	2	8	48.2
Meropenem	≤0.03-2	0.5	1	75.9
Clindamycin	≤0.03->8	0.06	>8	34.8
Doxycycline	≤0.06->8	0.12	8	40.6
SXTa	≤0.25->8	8	>8	86.6
Levofloxacin	≤0.5->8	1	>8	21.0

^aTested in a 1:19 ratio of trimethoprim to sulfamethoxazole.

^bNA, not applicable.