Fig. 1.

PCN treatment represses mRNA levels of Cpt1a and Hmgcs2 in fasting mice. Cr1: CD-1 (ICR) BR male mice were intraperitoneally injected with PCN (20 mg/kg of body weight) or DMSO, and were either fed at libitum or fasted with drinking water for 24 hours. The mRNA levels in these mouse livers were determined by real-time RT-PCR and were expressed by taking those in the fed mice treated with DMSO as one. Values express mean ± standard deviations (n=4). *p< 0.005 for vehicle injected fasted group vs PCN injected fasted group. # p<0.005 for vehicle injected fed group vs PCN injected fed group.