TABLE 3.
Darker-staining deletion strains
| Functiona | Gene(s)b |
|---|---|
| Purine biosynthesis | ADE1, ADE2, ADE4, ADE5, 7, ADE6, ADE8 |
| Stress response | RTS1 |
| Tryptophan biosynthesis | TRP3, TRP4, TRP5 |
| Amino acid metabolism | GCV1, GCV2 |
| Protein metabolism | DOA1, GCN1, UBP14 |
| ATP synthesis | ATP11, CUP5 |
| Sporulation | EMI5, RMD11 |
| Transcription | DAL81, RPA34, SNF12, SNF5, SSN8 |
| Secretion | GOS1, SSO1 |
| Gluconeogenesis | CAT8 |
| Meiosis | CBC2, UME6 |
| Chaperone regulator | HLJ1 |
| Chromatin structure | HHT2, SPT7 |
| mRNA splicing | LEA1, MUD1 |
| Zinc metabolism | IZH3 |
| Elongator complex subunit | IKI3 |
| Nitrogen transport | NPR2 |
| Glutathione biosynthesis | GSH1 |
| Mitochondrial function | YIA6 |
| Vacuolar acidification | TFP1, VMA4, VMA5, VMA10, VMA13, VMA21, VMA22, VPH2 |
| Methionine metabolism | CYS4, HOM2, HOM6, MUP1, MET17, MET31, SAM1, SAM2 |
| Protein binding | ATG19 |
| Phospholipid metabolism | DPL1 |
| Thiamine metabolism | THI2 |
| Oxidative stress response | MXR1 |
| Polyamine transport | TPO2 |
| Histone acetylation | SGF73 |
| Metal transporter degradation | TRE1 |
| Protein folding | ALF1 |
| ABC transporter | MDL2 |
| Fatty acid elongase | FEN1 |
| Fatty acid metabolism | SUR4 |
| Actin filament organization | SIW14 |
| Serine biosynthesis | SER33 |
| Nuclear fusion | VIK1 |
| Purine-cytosine transport | FCY22 |
| RNA polymerase II transcription factor | CUP9 |
| NADH kinase | POS5 |
| Enzyme regulator | RAI1 |
| Unknown | FMP49, TED1, YHI9, YBR239C, YCL007C, YDR008C, YDR048C, YDR095C, YKL118W, YLR358C, YMR244W, YOL138C, YOL075C, YOR331C, YPR115W |
a
Function as determined from Saccharomyces Genome Database (http://www.yeastgenome.org/).
b
Underlined genes of unknown function are listed as “dubious” in the database. Of the dubious genes, only YOR331C overlaps with another gene (VMA4) that impacts H2S production.