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Overexpression of LMP2B decreases the degree of BCR stimulation required to induce lytic EBV infection, in contrast to overexpression of LMP2A. BZLF1 mRNA expression in Akata-vector control (▪), Akata-LMP2A (•), or Akata-LMP2B (▴) 24 h after BCR cross-linking using increasing doses of anti-IgG. Means and SD are from three independent stimulation experiments on one representative polyclonal population.
