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. 2007 Dec 5;82(4):1739–1747. doi: 10.1128/JVI.01723-07

FIG. 7.

FIG. 7.

LMP2B restores calcium mobilization in LMP2A-overexpressing Akata cells. Calcium levels were determined before and after BCR cross-linking, and the kinetics were measured for 5 min. Upper panels, calcium mobilization after BCR cross-linking in Akata control cells and, as an additional control, in Akata cells with epigenetic overexpression of an unspecific protein in the cytosol (see Materials and Methods). Middle panels, calcium mobilization after BCR cross-linking in Akata-LMP2B cells without (2B) and with (2B + At) transiently transfected LMP2A. Lower panels, calcium mobilization after BCR cross-linking in Akata-LMP2A cells without (2A) and with (2A + Bt) transiently transfected FLAG-LMP2B. Baselines were measured just before BCR cross-linking. The percentage of responding cells was calculated as described in Materials and Methods.