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. 2007 Dec 12;82(4):1798–1807. doi: 10.1128/JVI.02256-07

TABLE 2.

Genetic polymorphism of HA gene of H5N1 virus

Group Virusa Clade Residue at the indicated antigenic site and positionb:
Site E
Site B
RBS
Site A
Site B
Glyco
Site B
Site D
Site E
Site C
86 94 124 129 138 140 155 156 174 181 183 189 212 227 263 269 277 282 310 322
A Ck/HK/YU22/02 8 A D N S Q K S S V P D R K E A L K M R Q
Ck/IDN/2A/04 2.1 A N D S Q K S T V P D R K E A L K M R Q
Dk/IDN/MS/04 2.1 A N D S Q K S A V P D R K E A L K M R Q
Ck/Salatiga/BBVet- IV/05 2.1 A N D S L R S S V P D R K E A L K M R Q
Ck/Malang/BBVet- IV/04 2.1 A N N S Q K S A V P D R K E A L K M R Q
HK213/03 1 A D S L Q K N A V P D R K E A L K M R Q
Ck/Bantul/BBVet-I/05 2.1 A N D S Q K S T V P D R K E A L K M R Q
Ck/YN/115/04 2.4 A N D S L R S S V P D R K D A L K V R Q
B Gs/GX/2112/04 5 A D N S Q R S A V P D K K E A L K M R Q
Ck/Jogjakarta/BBVet-IX/04 2.1 A S D S L R S T V P D K K E A L K M R Q
Dk/Vietnam/283/05 1 V D S L Q R S T I P D R R E T L K M R Q
Dk/HK/821/02 1 A D S L Q K S A V P D R K E A L K M R Q
Ck/Malaysia/5858/04 1 V D S L Q K S T V P D K R E T L K M R Q
VNM/1194/04 1 V D S L Q K S T V P D K R E T L K M R Q
VNM/1203/04 1 V D S L Q K S T V P D K R E T L K M R Q
Dk/VNM/N-XX/04 1 V D S L Q K S T V P D K R E T L K M R Q
Dk/VNM/S654/05 1 V D S L Q K S T V P D K R E T L K M R Q
MDk/JX/1653/05 9 A D N S L K S A V P D K K E A L K M R Q
Dk/Fujian/897/05 9 A D N S L K S A V P D K K E A L K M R Q
Gs/GY/337/06 4 A D N L L E S S V P D K T E A L K M R Q
Gs/YN/5539/05 7 A D N L L K N T V P D K K E A L K M R Q
C IDN/5/05 2.1 T S D S L S S T V P D R K E A L K M R Q
BH goose/QH15/05 2.2 A N D S Q R N A V P D R K E T L K I R Q
Gf/ST/1341/06 2.2 A N D S Q R N A V P D R K E T L K I R Q
MDk/JX/2295/05 2.2 A N D S Q R N A V P D R K E T L K I R Q
Ck/HN/999/05 2.3 V N D S Q K N A V P D R K D A V K M K Q
Dk/HN/157/05 2.3 V N D S Q K N A V P D R K D A V K M K Q
Ck/ST/4231/03 2.2 A N D S Q R S T V P D R K E A L K I R Q
Dk/GX/951/05 2.3 A N D L Q S N A V P D R K D A V K M K Q
Dk/HN/1265/05 2.3 A N D L Q S N A V P D R K D A V K M K Q
D Ck/GX/2439/04 5 A D N S Q R S A V P D K R X A L K M R Q
Qa/Gx/575/05 2.3 A N D L Q S N A V P D R K D A V K M K Q
Common Magpie/HK/645/2006 2.3 A N D S Q T N T I S D K K D A V K I K L
Oriental Magpie Robin/HK/366/2006 2.3 A N D S Q T N T I S D K K D A V K I K L
Ck/HK/282/2006 2.3 A N D S Q T N T I S D K K D A V K I K L
White eye/HK/737/07 2.3 A N D S Q T N T I S D K K D A V K I K L
SZ/406H/2006 2.3 A N D S Q T N T I S D K K D A V K I K L
Dk/VNM/568/05 2.3 A N D L Q N D A V P D R K D A V K M K Q
Peregrine-falcon/HK/1143/07 2.3 A A N L Q N S A V P D R K D T V R M R Q
Dk/HN/101/04 2.3 A N D S Q K N A V P D R K D A V K M K Q
CP heron/HK/18/05 2.3 A N N V Q S N A V P N M K D A V R M K Q
Consensus A N D S Q K S V P D R K E A L K M R Q
a

Abbreviations: FJ, Fujian; GD, Guangdong; Gs, goose; GX, Guangxi; GY, Guanyang JX, Jiangxi; MDk, migratory duck; MYS, Malaysia; Qa, quail; Rb pochard, rosybilled pochard; SCk, silky chicken; SZ, Shenzhen (see also text); Glyco, glycosylation.

b

The amino acid residue positions are derived from mature H5 sequence. Residues in boldface indicate polymorphisms in the HA sequence of the H5N1 viruses compared with the consensus sequence.