TABLE 4.
Comparison of antigenicity of recombinant viruses in neutralization assay using MAbs
| Virus | Neutralization titer of the indicated MAb by classa
|
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| I
|
II
|
III
|
|||||||||||||||
| 20A11 | 16F13 | 13D4 | 16G3 | 14E4 | 20H2 | 3C8 | 9H12B | 16A12 | 14D4 | 1G2 | 3F1B8 | 16F8 | 4GE1 | 1D8 | 6CF3 | 10DD2 | |
| VNM/1194/04 | 12,800 | 3,200 | 12,800 | 12,800 | 6,400 | 12,800 | 1,600 | 1,600 | 1,600 | < | < | < | < | < | < | < | < |
| rc-VNM/1194/04-6a | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 1,600 | 12,800 | < | 12,800 | 12,800 | 12,800 | < | 3,200 | 12,800 | 12,800 |
| rc-VNM/1194/04-189 | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 400 | < | 200 | 200 | < | < | < | < | < | < |
| CP heron/HK/18/05 | < | < | < | < | < | < | 100 | 800 | < | 12,800 | 12,800 | 1,600 | 100 | < | < | < | 1600 |
| rc-CP heron/HK/18/05 | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 12,800 | 3,200 | 200 | < | 12,800 | 12,800 | 12,800 | 12,800 | 400 | 12,800 | 12,800 | 12,800 |
a
Same panel of MAbs as in Table 1. rc, recombinant; <, <100.