TABLE 5.
Comparison of antigenicity of recombinant viruses in HI test using ferret antiseruma
| Virus | HI titer of the indicated virus in ferret antiserum:
|
||||
|---|---|---|---|---|---|
| Dk/HN/101/04 (clade 2.3) | BH goose/ QH/1A/05 (clade 2.2) | IDN/5/05 (clade 2.1) | VNM/1203/04 (clade 1) | Swan/Mongolia/244/05 (clade 2.1) | |
| Dk/HN/101/04 | 640 | 2,560 | 1,280 | 80 | 320 |
| BH goose/QH/1A/05 | 320 | 640 | 640 | 40 | 320 |
| IDN/5/05 | 80 | 320 | 1,280 | 40 | 40 |
| VNM/1203/04 | 80 | 80 | 160 | 160 | <40 |
| CP heron/HK/18/05 | 80 | 80 | 80 | 40 | <40 |
| rc-CP heron/HK/18/05 | 320 | 1,280 | 1,280 | 80 | 160 |
| VNM/1194/04 | <40 | <40 | 80 | 80 | <40 |
| rc-VNM/1194/04-6a | 320 | 640 | 1,280 | 80 | 80 |
| rc-VNM/1194/04-189 | 80 | 160 | 640 | 80 | 40 |
a
Values in italics are HI titers with homologous H5N1 strains which were used to generate ferret antiserum. Viruses and values in boldface are genetically modified H5N1 viruses described in this study and their respective HI titers.