FIG. 5.

Cytoplasmic redistribution of host nuclear proteins. Uninfected cells (mock) or HeLa cells infected with poliovirus for 4.5 h were fixed and stained with an antibody directed against nucleolin. The left-hand panels show phase-contrast images of the cells (phase), while the right-hand panels show nucleolin staining of the same field (nucleolin). +GuHCl, cells treated with 2 mM GuHCl. Cx, cells treated with 100 μg of cycloheximide/ml. GuHCl and cycloheximide were added 1 h after virus adsorption.