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. 2007 Dec 26;28(5):1541–1552. doi: 10.1128/MCB.01359-07

FIG. 7.

FIG. 7.

(A) Normal CTL generation in response to LCMV. Two pairs of CARD6+/+ and CARD6−/− littermates were infected with 2,000 PFU LCMV, and splenocytes were isolated at 8 days postinfection and evaluated for cytotoxicity against GP33-pulsed EL4 cells. (B) Comparable LCMV titers. CARD6+/+ and CARD6−/− littermates were intravenously infected with 2,000 PFU LCMV, and LCMV titers in spleens were determined at 3 days postinfection. (C) Equivalent response to MAV-1. CARD6+/+ and CARD6−/− littermates were infected intraperitoneally with 1,000 PFU MAV-1, and relative MAV-1 DNA expression in spleens and brains was determined by quantitative PCR at the indicated days postinfection.