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. 2007 Dec 17;28(5):1480–1488. doi: 10.1128/MCB.00651-07

FIG. 5.

FIG. 5.

Neuronal migration in the cerebral cortex of nestin-Cre; Gna12/; Gna13flox/flox embryos. Pregnant mice were injected at E12.5 (A) or E15.5 (B) with BrdU, and the distribution of BrdU-labeled neurons was determined in wild-type (WT) and nestin-Cre; Gna12/; Gna13flox/flox (KO) embryos at E18.5. Neurons born at both E12.5 and E15.5 took part in the formation of neuronal ectopia. The broken lines mark the surface of the developing brain. Areas containing ectopic neurons are marked by stars. Bar lengths are 125 μm (upper panels in A and B) and 62.5 μm (lower panels in A and B).

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