TABLE 2.
Comparison of BCC virulence in different infection models
| Species and strain | LD50 in G. mellonella | % Alfalfa seedlings with symptomsa | Virulence in rats (% with pathology on day 7 p.i.)a | C. elegans pathogenicity scoreb |
|---|---|---|---|---|
| B. cepacia strains | ||||
| Cep509 | 30 | 85 ± 18c | 43.0 ± 2.0c | 0 |
| ATCC 17759 | 1 | 73 ± 13 | NDd | ND |
| B. multivorans strains | ||||
| C5393 | >3,000,000 | 0 | 13.3 ± 5.9 | 0 |
| C3430 | >3,000,000 | ND | ND | 0 |
| C5274 | 1,000,000 | ND | ND | 0 |
| C5568 | >3,000,000 | ND | ND | 1 |
| B. cenocepacia strains | ||||
| PC715j | 4,000 | 80 ± 18 | 22.8 ± 10.8 | ND |
| J2315 | 100,000 | 65 ± 10 | 38.0 ± 21.0 | 1 |
| K56-2 | 900 | 100 ± 0 | 40.5 ± 4.2 | 3 |
| C1257 | 40,000 | ND | ND | ND |
| C4455 | 100,000 | ND | ND | 1 |
| C5424 | 200,000 | ND | ND | 0 |
| C6433 | 30,000 | ND | ND | ND |
| Cep511 | 80,000 | 98 ± 3 | 12.7 ± 1.53 | 0 |
| B. stabilis strains | ||||
| ATCC BA-67 | 2,000,000 | 13 ± 12 | 16.0 ± 5.6 | 0 |
| C7322 | >2,000,000 | 10 ± 17 | ND | 0 |
| B. vietnamiensis strains | ||||
| DBO1 | 200,000 | ND | ND | ND |
| PC259 | >3,000,000 | 7 ± 6 | 19.7 ± 0.6 | 1 |
| B. dolosa strains | ||||
| AU0645 | >4,000,000 | 25 ± 0 | ND | 1 |
| STM1441 | 40,000 | ND | ND | 2 |
| B. ambifaria strain | ||||
| Cep0996 | 800,000 | 53 ± 16 | ND | 3 |
| B. anthina strain | ||||
| J2552 | 300,000 | ND | ND | 3 |
| B. pyrrocinia strain | ||||
| ATCC 15958 | 300 | ND | ND | 3 |