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Amino acid substitutions
| Region | Amino acid substitution(s) (n)a
|
|
|---|---|---|
| Inner loop | Outer loop | |
| N terminus | None (0) | NA |
| Loop 1 | H58Y, S59T, D63N, M74L (4) | D31R (1) |
| Loop 2 | V137I (1) | A95S, A103E, S108F, E112D (4) |
| Loop 3 | K208N, Q210S, M215V (3) | F166I, T167K, V178L, V181S (4) |
| Loop 4 | None (0) | D242N, S245A, Q256E (3) |
| Loop 5 | NA | K334Y, V335A, E336A, M337K (4) |
| C terminus | K363R, Q364H, R365G (3) | NA |
n, number of substitutions; NA, not applicable.
