Schematic of chimeric recombinant RVs with components of the highly pathogenic SB strain (gray boxes) and the nonpathogenic SN strain (white boxes). SN-BM, SN-BG, and SN-BMBG were constructed by the replacement of the M or G gene or both M and G genes in the SN backbone with the corresponding genes of SB. LS, leader sequence; TS, trailer sequence; ψ, pseudogene.