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Similar binding pattern of ICP4, polII, and TBP to the ICP8 promoter in KOS-, LS-29-18-, and gCInr-infected cells. ChIP analysis was conducted on KOS-, LS-19-18-, and gCInr-infected cells at 4 and 8 h postinfection to examine ICP4, TBP, and polII binding to the ICP8 promoter. (A) Percentage of genomes bound at 4 and 8 h postinfection in the absence of PAA. (B) Percentage of genomes bound at 4 and 8 h postinfection in the presence of PAA.
