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. 2008 Jan 16;82(6):2883–2894. doi: 10.1128/JVI.01805-07

FIG. 1.

FIG. 1.

Aromatic amino acids in the JMDs of enveloped viruses. (A) Amino acid sequences of the JMDs were aligned according to the predicted TMs, predicted by several computer algorithms: TMpred (http://www.ch.embnet.org/software/TMPRED_form.html), DAS, HMMTOP, and SOSUI (http://sosui.proteome.bio.tuat.ac.jp/about-sosui.html). Aromatic amino acids are highlighted in bold. (B) Conserved amino acid sequences in the JMDs of diverse coronavirus spike glycoproteins were aligned based on the consensus KWPWYVWL sequence obtained from CLUSTALW. Identical amino acids are shaded, and aromatic amino acids are displayed in bold. GenBank accession numbers are as follows: SARS-CoV, P59594; murine hepatitis virus A59 (MHV-A59), AAR92026; infectious bronchitis virus (IBV), AAO34396; HIV type 1 (HIV-1), AAR05826; HIV type 2 (HIV-2), 2105299E; Moloney murine leukemia virus (MoMuLV), AAQ95285; Mason-Pfizer monkey virus (MPMV), NP_056894; Ebola virus, AAA96744; Marburg virus, ABE27015; VSV, NP_955548); influenza HA (Flu HA), ABP49228; Sendai virus, AAC82296; and Sindbis virus, CAA24684.