FIG. 4.

Reasons driving discordant responses. Three reasons (a, b, and c) were identified to explain discordant responses. Here, examples for each of the reasons are shown. Patient identification, HLA haplotype, and autologous viral sequence (numbers at the left indicate the amino acid positions) are shown together with the primary sequences of reactive and nonreactive peptides. Putative minimal epitopes are shown boxed, and the putative restricting HLA alleles are also indicated. In panel c, the anchor position is denoted with an asterisk.