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. 2008 Jan 29;98(4):832–839. doi: 10.1038/sj.bjc.6604211

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Copyright © 2008 Cancer Research UK

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5-Fluorouracil and folate metabolic pathways. Genes examined in our study are shown in bold. DPD, dihydropyrimidine dehydrogenase; DHFR, dihydrofolate reductase; MTHFR, methylenetetrahydrofolate reductase; OPRT, orotate phosphoribosyl transferase; TS, thymidylate synthase; TP, thymidine phosphorylase; . The official Human Genome Organization gene nomenclature is used. Common or alternative names for each gene can be found at http://pharmacogenetics.wustl. edu.