Table 3. Toxicity to gefitinib and 5-FU.
Safety analysis set (n=24)
|
||
---|---|---|
Toxicity, n (%) | Grade 1 or 2 | Grade 3 or 4 |
Gefitinib | ||
Rash | 5 (20.8) | 0 |
Diarrhoea | 3 (12.5) | 0 |
Erythema | 3 (12.5) | 0 |
5-FU | ||
Diarrhoea | 7 (29.2) | 0 |
Stomatitis | 4 (16.7) | 1 (4.2) |
Nausea | 4 (16.7) | 0 |
Alopecia | 3 (12.5) | 0 |
Erythema | 3 (12.5) | 0 |
Gefitinib/5-FU combination | ||
Diarrhoea | 4 (16.7) | 0 |
Fatigue | 4 (16.7) | 0 |
Nausea | 3 (12.5) | 1 (4.2) |
5-F=5-fluorouracil.