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. 2008 Feb 5;98(4):716–719. doi: 10.1038/sj.bjc.6604232

Table 3. Toxicity to gefitinib and 5-FU.

  Safety analysis set (n=24)
Toxicity, n (%) Grade 1 or 2 Grade 3 or 4
Gefitinib    
 Rash 5 (20.8) 0
 Diarrhoea 3 (12.5) 0
 Erythema 3 (12.5) 0
     
5-FU    
 Diarrhoea 7 (29.2) 0
 Stomatitis 4 (16.7) 1 (4.2)
 Nausea 4 (16.7) 0
 Alopecia 3 (12.5) 0
 Erythema 3 (12.5) 0
     
Gefitinib/5-FU combination
 Diarrhoea 4 (16.7) 0
 Fatigue 4 (16.7) 0
 Nausea 3 (12.5) 1 (4.2)

5-F=5-fluorouracil.