Table 2. Treatment delivery.
| IP (n=54) | IPE (n=55) | |
|---|---|---|
| No. (%) | No. (%) | |
| Number of cycles delivered | ||
| 6a | — | 1 (2) |
| 4 | 41 (76) | 36 (65) |
| 3 | 6 (11) | 6 (11) |
| 2 | 3 (6) | 6 (11) |
| 1 | 4 (7) | 6 (11) |
| Reasons for termination of the treatment † | ||
| Completion | 40 (74) | 35 (64) |
| Disease progression | 9 (17) | 2 (4) |
| Toxicity | 3 (6) | 13 (24) |
| Patient refusal | 2 (4) | 4 (7) |
| Others | 0 (0) | 1 (2) |
| Total number of cycles delivered | 192 (100) | 186 (100) |
| Total number of omission on day 8 | 35 (18) | 37 (17) |
| Total number of cycles with dose reduction | 28 (15) | 31 (17) |
†P=0.013 by χ2 test.
a
Protocol violation.