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. 2008 Jan 14;153(4):751–759. doi: 10.1038/sj.bjp.0707619

Figure 6.

Figure 6

Responses to isoprenaline following β1- or β2-adrenoceptor blockade. Consecutive applications of isoprenaline and/or isoprenaline plus blocker and washout periods (a). β1-Adrenoceptor-selective blockade with 0.3 μM CGP 20712A, n=11 (b). β2-Adrenoceptor-selective blockade with 50 nM ICI 118,551, n=13, (c). Two consecutive applications of isoprenaline in the absence of antagonist (***P<0.001 vs preceding basal/wash; ##P<0.01, ###P<0.001 vs Iso 1; *P<0.05 vs basal; all tests paired). For (a and b), there was no significant difference between Basal/Wash 1/Wash 2.