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Muscarinic inhibition of beating frequency under basal and isoprenaline-stimulated conditions. Rate, beats per min (b.p.m.) relative to basal. Beating rate drops significantly after carbachol (CCh) application under basal conditions (10 μM, ***P<0.001, n=12) and in the presence of 100 nM isoprenaline (**P<0.02, n=9).
