Figure 1.

IL-1β-induced IL-6 synthesis in primary cortical neurones. Cultures were treated with vehicle (C) or IL-1β (0.03–30 U ml⁻¹) for 7 h, and cell lysates and supernatants were collected and assayed for IL-6 using a mouse-specific ELISA. Data are presented as the mean±s.d. of seven independent experiments ^*P<0.05, ^**P<0.01, ^***P<0.001, IL-1β vs control. IL, interleukin.