Figure 2.

Cell toxicity induced by isoniazid (INH) on human hepatocytes in monolayer and gel entrapment cultures. The hepatocytes were incubated with 0.037, 0.07 and 0.11 mM isoniazid for 72 h, whereas the groups without isoniazid treatment were used as control. The results were assessed by cell viability (a), intracellular glutathione (GSH) content (b) and human albumin secretion (c). Data are given as mean±s.d. (n=3); ^*P<0.05, ^**P<0.01 (compared to controls).