Table 3.

Taste preference thresholds of B6 and 129 inbred and 129.B6-Tas1r3 congenic mice

	Parental Strains				Congenic Mice
Taste Compound	B6	Difference	129	Reference	B6/129*	Difference	129/129*	Tas1r3 Effect on Intakes or Preferences†
Saccharin, mM	1	<	10	10	0.6	<	5	+
Acesulfame, mM	1	<	10	10	3	<	ND	+
Sucralose, mM	0.25	<	2.5	10	0.3	<	10	+
SC-45647, mM	0.03	<	0.3	10	0.09	<	0.3	+
Sucrose, mM	29	<	234	10	30	<	100	+
Maltose, mM	28	<	83	10	100	<	300	+
Glucose, mM	10	=	10	1	300	<	ND	+
Fructose, mM	10	<	30	1	30	<	ND	+
Erythritol, mM	246	<	ND	10	ND	=	ND	+
Polycose, %	0.3	<	3	7	1	=	1	−
Maltooligosaccharide, %	0.1	<	3	1	3	=	3	−
d-Tryptophan, mM	1	<	ND	10	30	<	ND	+
d-Phenylalanine, mM	3	<	ND	10	30	<	ND	+
l-Proline, mM	100	<	ND	10	100	<	ND	+
l-Glutamine, mM	100	<	300	1	ND	=	ND	−
l-Threonine, mM	30	<	100	1	ND	=	ND	−
l-Alanine, mM	10	<	100	1	ND	=	ND	−
Glycine, mM	0.1	<	300	10	ND	=	ND	−

Signs<, >, and = indicate presence and direction of threshold differences. ND, not determined (highest concentration tested was below preference threshold). Taste preference threshold was defined as the lowest solution concentration for which animals display preference score of at least 75%. Thresholds reported in References 7 and 10 were defined with a different criterion and in some cases differ from threshold values shown in this table. Data for congenic mice are from the present study. *Tas1r3 genotypes. †Tas1r3 effect on intakes or preferences as reported in Table 5.