Figure 2.

CatFam performance evaluation. The performance of CatFam is measured by precision and recall, which are defined as precision = TP/(TP+FP) and recall = TP/(TP+FN), where TP, FP and FN represent the number of true-positive, false-positive, and false-negative predictions, respectively. A total of 18,949 proteins, not used for profile generation, are used to evaluate two CatFam databases, CatFam-3D and CatFam-4D, which predict 3-digit and 4-digit EC numbers for query proteins, respectively. The results are sorted according to the maximum sequence identity between the query protein and the proteins used for profile generation.