Table 4.

Studies measuring circulating celecoxib levels

Population	Subjects	Weeks On Drug	Dose (mg)1	Last Dose (hrs)2	Source	Celecoxib concentration (ng/mL)
Healthy Adults [18]	8	2	200 b.i.d.	up to 25	serum	437
Healthy Adults [18]	35	2	40 q.d.	13	plasma	568
Healthy Adults [18]	24	2	200 b.i.d.	up to 24	plasma	500
Healthy Adults [20]	35	6	400 q.d.	13	plasma	601
Elderly Adults [21]	8	1	200 b.i.d.	2	plasma	755
Pediatric cancer patients [22]	9	250 mg/kg	b.i.d.	6	plasma	668
Adult cancer patients [23]	4	week3	400 b.i.d.	6–8	plasma	1087

1: b.i.d.: twice daily; q.d.: once daily

2: Unless otherwise stated, average time from last dose celecoxib to blood draw

3: The text did not define how many weeks the subjects took the medication