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. 2007 Dec 21;6:81. doi: 10.1186/1476-4598-6-81

Figure 3.

Figure 3

CD44 expression is dependent on Fra-1 and the pathways that control Fra-1 expression. (A) Western blot showing the effect of the PI3K and Src inhibitors in the CD44 expression of an SV40+ and SV40- cell line. (B) Western blots showing that CD44 expression in the SV40- MM line follows the pattern of its Fra-1 expression. The use of a dominant negative construct for Fra-1 (dnFra-1) decreases CD44 expression, but not further decreases are observed after PD98059 or LY294002 is added to the dnFra-1 stable cell line.