Table 3.

Free radical reactions of

Dismutase activity
1	SOD−Cu2+ + O2⨪ → SOD−Cu+ + O2
2	SOD−Cu+ + O2⨪ → SOD−Cu2+ + H2O2
3
Peroxidase activity
4	SOD−Cu2+ + H2O2 ⇌ SOD−Cu+ + O2⨪ + 2H+
5	SOD−Cu+ + H2O2 → SOD−Cu2+−⋅OH + OH−
6	SOD−Cu2+−⋅OH + His-61 → His⋅ + SOD−Cu2+ + H2O
7	SOD−Cu2+−⋅OH + HCO2− → SOD−Cu2+ + CO2⨪ + H2O
8	SOD−Cu2+−⋅OH → inactive SOD (Enz−Cu2+ + 2-oxohistidine)
Hydroxyl radical generating activity
9	Enz−Cu2+ + H2O2 → Enz−Cu+ + O2⨪ + 2H+
10	Enz−Cu+ + H2O2 → Enz−Cu2+ + ⋅OH + OH−
Nitration of tyrosine
11	SOD−Cu2+ + ONOO− → SOD−CuO....NO2+
12	SOD−CuO....NO2+ + Tyr → SOD−Cu2+ + OH− + NO2-Tyr