Table 1.
Neutralization in single cycle assays (50% inhibitory concentrations (μg/ml))a
LAI (whole virus) | JR-FL (pseudovirus) | |||
wt | N386D | wt | N386D | |
2G12 | 1.93 | >10 | 0.66 | 7.96 |
CD4-IgG2 | 0.78 | 0.28 | 0.17 | 0.11 |
b12 | 0.62 | 0.079 | 0.043 | 0.020 |
b6 | >10 | >10 | >10 | >10 |
a The IC50 values were derived from the experiment in fig. 6 as described in the materials and methods section.