Skip to main content
. Author manuscript; available in PMC: 2008 Mar 3.
Published in final edited form as: J Cereb Blood Flow Metab. 2005 Sep;25(9):1138–1149. doi: 10.1038/sj.jcbfm.9600121

Figure 4.

Figure 4

Minocycline treatment does not change the volume of the remaining and uninjured tissue of lesioned hemisphere 7 days after transient MCA occlusion. Volumes of the contralateral hemisphere, remaining ipsilateral and morphologically preserved ipsilateral hemisphere were determined in eight consecutive 15-µm-thick paraffin-embedded cresyl violet-stained coronal sections. Sections were obtained at 400-µm intervals. Volumes of the remaining ipsilateral (A) and morphologically normal/unaffected (B) tissues were normalized to the volume of contralateral hemisphere in serial sections. Pups treated with a single or triple minocycline injections show no difference in the volume of the remaining (A) or preserved (B) tissue in the hemisphere ipsilateral to the occlusion.