Table 1.
Characteristics of genes modulated by ASP
| Band name | ASP treatment, % control ± SD | P vs. control | Probe size, bp | mRNA size, kb | DNA sequence homology by blast search | Sequence identity |
|---|---|---|---|---|---|---|
| Down-regulated genes | ||||||
| ASP-D1 | 62 ± 25 | <0.02 | 298 | 1.8 | Murine tyrosinase | 99% |
| ASP-D2 | 63 ± 18 | <0.01 | 366 | 2.6 | Murine TRP2 | 98% |
| ASP-D3 | 84 ± 12 | <0.05 | 608 | 4.8 | Murine dystroglycan | 98% |
| ASP-D4 | 68 ± 21 | <0.02 | 614 | 1.8 | β-subunit of murine TCP- containing chaperonin complex | 99% |
| ASP-D5 | 77 ± 18 | <0.05 | 696 | 2.6 | Homology to an EST 3′-directed murine cDNA | 100% |
| ASP-D6 | 80 ± 13 | <0.05 | 409 | 6.6 | Human KIA A0261 | 71% |
| Up-regulated genes | ||||||
| ASP-I1 | 178 ± 18 | <0.02 | 340 | 2.3 | Murine MCM6 | 99% |
| ASM-I2 | 196 ± 28 | <0.02 | 704 | 6.5 | Murine ITF2 | 100% |
| ASP-13 | 133 ± 18 | <0.02 | 410 | 6.2 | Homology to 3 ESTS human retina cDNAs | 90% |