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. 2008 Mar 12;3(3):e1781. doi: 10.1371/journal.pone.0001781

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Residues are displayed as the subtype B consensus; other residues found among sequences analyzed are shown below each consensus residue. Numbers shown in subscript for each residue represent total number of sequences analyzed (in the consensus sequence) and frequencies in viruses (other residues) from drug-naïve (left) and NRTI-treated (right) subjects. Residues which differed significantly (p<0.05) in frequency between naïve and treated patients, as well as the corresponding changed residues, are boxed in gray.