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. 2008 Mar 12;3(3):e1754. doi: 10.1371/journal.pone.0001754

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Meczes et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: Decatenation activity of all proteins, each column is the mean of at least two independent experiments. Standard errors are shown, with significant difference from full length enzyme marker with ‘***’. B: Representative cleavage experiment with 4.3 kb linearised pBR322 DNA with all proteins in the presence of mitoxantrone. TopoIIβ proteins in this case carry the S165R mutation.