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. 2008 Mar 12;3(3):e1746. doi: 10.1371/journal.pone.0001746

Table 1. Childhood obesity case-control association study results for FTO region markers perfectly correlated with rs9939609 in Caucasians (bold) plus all other markers present on the BeadChip in the corresponding HapMap CEU region of LD in our (a) Caucasian and (b) African American cohorts respectively.

(a) Caucasians
Chr SNP r2 to rs9939609 B35 location Minor Allele Major Allele Aff MAF (n = 418) Ctrl MAF (n = 2270) OR 95% CI P-value
16 rs9930333 0.843 52357478 T G 0.476 0.425 1.228 1.058–1.427 0.0070
16 rs10852521 0.584 52362466 T C 0.422 0.484 0.779 0.670–0.906 0.0011
16 rs16945088 0.099 52370025 G A 0.094 0.090 1.056 0.818–1.365 0.68
16 rs8050136 1 52373776 A C 0.448 0.391 1.266 1.088–1.471 0.0022
16 rs3751812 1 52375961 T G 0.443 0.386 1.267 1.089–1.473 0.0022
16 rs12597786 0.014 52378808 T C 0.026 0.020 1.320 0.815–2.138 0.26
16 rs9931164 0.022 52382739 G A 0.020 0.019 1.024 0.597–1.756 0.93
16 rs9941349 0.9 52382989 T C 0.462 0.407 1.254 1.080–1.457 0.0030
16 rs7199182 - 52383621 G A - - - - -
16 rs7190492 0.328 52386253 A G 0.296 0.354 0.767 0.651–0.903 0.0014
16 rs8044769 0.62 52396636 T C 0.414 0.483 0.758 0.652–0.881 0.00031
16 rs6499646 0.101 52401034 C T 0.103 0.092 1.141 0.890–1.462 0.30
16 rs1421090 0.026 52407671 C T 0.273 0.260 1.073 0.907–1.270 0.41

Minor allele frequencies (MAF), allelic test P-values, and odds ratios (OR) with 95% confidence intervals (CI) are shown for each SNP. rs7199182 has a MAF<1% in Caucasians so was not analyzed in that ethnicity. The ORs shown are for the minor allele. P-values are two-sided in each instance. r2 values to rs9939609 derived from (a) CEU and (b) YRI HapMap samples are also shown.