. Author manuscript; available in PMC: 2009 Feb 1.

Published in final edited form as: Bioorg Med Chem Lett. 2008 Jan 14;18(3):913–917. doi: 10.1016/j.bmcl.2007.12.048

Table 1.

Effect of salts on the formation of 14^a

Additive	Equivalents	Yield of 14 (%)
None	-	30
NaI	5	48
	10	50
KI	5	20
	10	27

Reactions were performed by slow addition (syringe pump, 1 h) of a solution of deprotected 13 (27 µmol) in DMF (10 mL) to a solution of BOP (1.5 equiv.), HOBt (1.5 equiv.), the salt, and iPr₂NEt (3 equiv.) in 20 mL of DMF at 0 °C.