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. Author manuscript; available in PMC: 2009 Feb 22.
Published in final edited form as: J Mol Biol. 2007 Dec 5;376(3):621–633. doi: 10.1016/j.jmb.2007.11.094

Figure 6. Intracellular location of CDR-4 in vivo.

Figure 6

Transgenic C. elegans that contain a cdr-4/CDR-4-eGFP expression vector, were fed RITC-dextran. The location of CDR-4-eGFP (GFP) and RITC-labeled lysosomes (rhodamine) were visualized using the appropriate filter sets. A false-color, composite image (merge) is presented that demonstrates the localization of CDR-4 in lysosomes. A higher magnified (400×) image of the identical transgenic C. elegans is presented in the insert. Locations where the eGFP and rhodamine signals are coincident can be identified by the yellow color. The lower panel indicates the location of CDR-4-eGFP within the pharynx of an adult C. elegans. The location of pharyngeal muscles cells; pm5, pm6, and pm 7; are indicated. Pm5 cells are columnar cells, which extend from the anterior region of the terminal bulb to the posterior of the metacorpus 62.