Table 2.

Adult lifespan of animals with age-1 expression restricted to neurons, intestine or muscle

Genotype	Mean (days)	Std error	(n)	Expt.	% shortened	P vs control a
Pan-neuronal (Pric-19: age-1)
age-1(+); bvIs2	13.3	0.48	73	13	20	<0.0001, <0.0001
age-1(+); bvIs2	14.4	0.65	56	13	14	0.2209, 0.0603
age-1(mg44); bvIs2	19.9	0.77	74	7	10	0.0010, 0.0319
age-1(mg44); bvIs2	24.3	1.37	45	8	8	0.1131, 0.2136
age-1(mg305); bvIs2	19.7	0.77	122	7	16	0.0003, 0.0961
age-1(mg305); bvIs2	21.3	1.02	44	13	58	<0.0001, <0.0001
age-1(+); bvEx125	15.5	0.62	42	13	7	0.5718, 0.0699
age-1(+); bvEx128	16.6	0.78	49	13	1	0.0335, 0.5328
age-1(mg44); bvEx11	17.8	0.88	45	1	21	0.0004, 0.0192
age-1(mg44); bvEx12	14.3	0.29	78	1	37	<0.0001, <0.0001
age-1(mg44); bvEx12	16.7	0.64	81	11	16	<0.0001, <0.0001
age-1(mg44); bvEx12	16.7	0.64	81	11	16	<0.0001, <0.0001
age-1(mg44); bvEx120	21.1	0.67	119	9	5	0.8562, 0.5176
age-1(mg44); bvEx121	21.9	0.43	85	9	1	0.0133, 0.1121
age-1(mg44); bvEx122	20.2	0.45	135	9	9	0.0001, 0.0028
age-1(mg44); bvEx123	19.3	0.56	92	9	13	<.0001, 0.0004
age-1(mg44); bvEx123	19.6	0.69	41	10	18	<0.0001, <0.0001
age-1(mg44); bvEx125	19.3	0.88	50	9	13	0.0091, 0.0095
age-1(mg44); bvEx125	17.4	0.90	49	10	27	<0.0001, <0.0001
age-1(mg44); bvEx125	19.0	0.54	61	13	4	0.0248, 0.1169
age-1(mg44); bvEx128	22.0	1.01	26	9	0	0.5992, 0.4764
age-1(mg44); bvEx128	16.6	0.78	49	13	16	0.0002, 0.0102
age-1(mg44); bvEx128	18.1	0.56	36	15	12	<0.0001, 0.0030
age-1(mg305);bvEx(ric-19: age-1)	26.0	1.14	79	3	20	<0.0001, <0.0001
Intestine(Pges-1: age-1)
age-1(mg44); bvIs1	20.5	0.72	50	8	22	<0.0001, <0.0001
age-1(mg305); bvIs1	21.3	1.05	47	1	6	<0.0001, <0.0001
age-1(mg305); bvIs1	27.0	1.06	77	3	17	<0.0001, <0.0001
Body muscle(Punc-54: age-1)
age-1(mg44); mgIs37	21.4	1.41	44	8	19	0.0057, 0.0067
age-1(mg305); mgIs37	19.7	0.85	45	1	34	<0.0001,<0.0001
age-1(mg305); mgIs37	23.6	0.99	75	3	27	<0.0001, <0.0001

^aLog-Rank, Wilcoxan, versus non-transgenic control.