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Schematic model for the action of Rab8-JRAB/ MICAL-L2 and Rab13-JRAB/MICAL-L2 complexes in the assembly of AJs and TJs. Whereas the Rab8-JRAB/MICAL-L2 complex resided at the PNC mediates the recycling of E-cadherin to the PM and the assembly of AJs, the Rab13-JRAB/MICAL-L2 complex resided at the PM regulates the recycling of claudins and occludin to the PM and the formation of TJs. N, nucleus.
