. Author manuscript; available in PMC: 2009 Feb 15.

Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jan 18;863(1):141–149. doi: 10.1016/j.jchromb.2008.01.018

Table 5.

BaP metabolite concentrations detected following two waterborne experiments (average ± SE ng/gallbladder). Values are not corrected for extraction recoveries.

Metabolites	BaP Doseμg/L	Experiment 1			Experiment 2
Metabolites	BaP Doseμg/L	F	G	S	F	G
BaP-7,8-dihydrodiol	10	nd	nd	nd	^*	12.4±6.8
BaP-7,8-dihydrodiol	100	7.0±1.7	^*	nd	13.6±3.5	13.1±3.2
BaP-1,6-dione	10	nd	14.4±4.8	nd	nd	64.5±19.8
BaP-1,6-dione	100	nd	20.2±2.8	^*	nd	103±15.0
BaP-3,6-dione	10	^*	10.1±3.0	nd	9.2±3.7	62.4±21.9
BaP-3,6-dione	100	^*	13.2±1.5	nd	4.7±2.5	84.8±12.5
BaP-6,12-dione	10	nd	nd	nd	nd	5.4±2.7
BaP-6,12-dione	100	nd	nd	nd	nd	3.8±0.5
3-hydroxy BaP	10	^*	34.1±19.2	nd	5.6±0.9	267±75.7
3-hydroxy BaP	100	^*	55.8±15.0	6.2±3.3	7.1±1.1	397±61.3

There was no BaP-9,10-dihydrodiol and 9-hydroxy BaP detected in any sample. F= free metabolites; G= Glucurase digestion released metabolites; S= Sulfatase digestion released metabolites.

nd: Not detected.

: Detectable, but lower than the linear range.

In experiment 1, there were 4 samples in low BaP group (10 μg/L), and 6 samples in high BaP group (100 μg/L); in experiment 2, there are 6 samples in low BaP group and 7 samples in high BaP group.