Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Interdomain hinges and conformational flexibility. An outline of the FAS dimer structure (red) was rotated 180° and the resulting outline (yellow) superimposed on the original. The active sites of the two structures are shown as red and yellow spheres and the possible location of hinges that could facilitate the conformational changes required to produce the two structures are shown as crossed circles. Reproduced with permission from ref. 88.
