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. 1998 Jun 23;95(13):7422–7426. doi: 10.1073/pnas.95.13.7422

Figure 3.

Figure 3

Effect of p38 MAPK inhibition on cell-associated and secreted p24 antigen. U1 cells were cultured for 24 hr in polypropylene tubes followed by assay for cell-associated (open bars) and secreted (stippled bars) HIV p24 antigen as described in Materials and Methods. Cells were cultured in the presence of IL-1β alone (10 ng/ml, control) or with IL-1β plus p38 inh at 4 μM or 0.008 μM. Results are expressed as percent change compared with stimulation with IL-1β alone (set at 100%). n = 3 separate experiments. ∗∗, P < 0.01; •, P < 0.001 compared with IL-1β alone.