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. 2007 Dec 13;116(3):340–348. doi: 10.1289/ehp.11005

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Effects of neonatal DZN exposure on indices of cell-packing density and total cell number. (A) DNA concentration (DNA per unit tissue weight). (B) DNA content (DNA per brain region). Abbreviations: bs, brain stem; f/p cx, frontal/parietal cortex; hp, hippocampus; mb, midbrain; st, striatum; t/o cx, temporal/occipital cortex. Data represent means ± SEs obtained from six animals of each sex in each treatment group at each age, presented as the percentage change from control values shown in Table 1. Values for males and females were combined because of the absence of interactions of treatment × sex or treatment × sex × other variables. Multivariate ANOVA for all factors (all treatments, both sexes, all ages, all regions) were performed. In (A), there was an overall main treatment effect (p < 0.02), with significant differences from the control restricted to the DZN 0.5 group (p < 0.009). Further subdivisions of the data were not examined because of the absence of interactions of treatment with the other variables. In (B), treatment × region is significant at p < 0.004, and lower-order ANOVAs for each region appear within the panel; subdivision into separate ages was not carried out because of the absence of an interaction of treatment × age.