. Author manuscript; available in PMC: 2009 Feb 28.

Published in final edited form as: J Ethnopharmacol. 2007 Nov 22;116(1):179–186. doi: 10.1016/j.jep.2007.11.019

Table 1.

Notoginseng selectively alters TLR-induced costimulatory molecule expression on DC2.4 cells.

	CD40^a	CD86
Unstimulated	192 ± 2	1224 ± 28
LPS	1484 ± 61^#	1630 ± 52^#
LPS + Notoginseng	932 ± 35^#^*	1295 ± 115^#^*
CpG	611 ± 34^#	1141 ± 33
CpG + Notoginseng	512 ± 13^#^*	1408 ± 28^#^*
Poly(I:C)	1627 ± 83^#	1366 ± 49^#
Poly(I:C) + Notoginseng	1098 ± 40^#^*	929 ± 2^#^*

DC2.4 cells were not stimulated or stimulated with LPS (1µg/ml), CpG (0.5µM) or poly(I:C) (12.5 µg/ml) and concomitantly treated with notoginseng (50 µg/ml) for 24 hours.

Mean Channel Fluorescence (MCF) was determined by flow cytometry. Data shown are representative of three independent experiments. Error bars indicate mean ± SEM of five samples

p<0.05 for the comparison of unstimulated and TLR-activated cells

p<0.05 for the comparison of TLR-stimulated cells treated with notoginseng or untreated